All brain tumour types brain tumour hub clinical trials

Relates to tumour types	Title of Research	Description	More information
Anaplastic astrocytoma	UKCRN ID 7007 NCRN064 SAPPHIRE - AP 12009 vs Temozolomide or BCNU in anaplastic astrocytoma	Interventional: drug Efficacy and safety of Trabedersen (AP 12009) in adult patients with recurrent or refactory anaplastic astrocytoma (WHO grade III) as compared to... read more	Click for more details and contact information
Anaplastic astrocytoma	EORTC protocol 26053-22054 (BR14): A randomised controlled trial of temozolomide as adjuvant or concurrent treatment in anaplastic (WHO grade III) glioma	Interventional: chemo and radiotherapiesThis study will establish whether concurrent RT and adjuvant temozolomide improves the outcome of patients with non-codeleted... read more	Click for more details and contact information
Meningioma	EORTC protocol 22042-26042. Adjuvant postoperative high-dose radiotherapy for atypical and malignant meningioma: a Phase II and observation study	Interventional: radiotherapy For malignant meningiomas. Radiotherapy dose will be escalated to 60 or 70Gy depending on the extent of resection and amount of residual... read more	Click for more details and contact information
Glioblastoma	Phase I trial of IMA950 multipeptide vaccine plus GMCSF in glioblastoma	Interventional: drug A Cancer Research UK Phase I trial of IMA950 (a novel multi-peptide vaccine) plus GM-CSF in patients with newly diagnosed glioblastoma. read more	Click for more details and contact information
Glioblastoma	NCT01310868 GALA5. Study of Polifeprosan 20 With Carmustine Implant (Gliadel) and fluorescence-guided radical tumour resection with Aminolevulinic Acid followed by adjuvant radiotherapy and Temozolomide in patients with primary glioblastoma.	Interventional: chemo and radiotherapy Drugs used in chemotherapy, such as Gliadel wafer and temozolomide, work in different ways to stop the growth of tumor cells,... read more	Click for more details and contact information
Glioblastoma	NCT01233492 Boron Phenylalanine with or without Mannitol in treating patients with Glioblastoma Multiforme	Interventional: drug. Giving boron phenylalanine in different ways and measuring it in tissue in patients with glioblastoma multiforme may help in planning better... read more	Click for more details and contact information
Glioblastoma	NCT01308684 A dose and efficacy study of RO5323441 in combination with Avastin (Bevacizumab) in patients with recurrent glioblastoma	Interventional: drug. This study will evaluate the safety and efficacy of RO5323441 in combination with Avastin (bevacizumab) in patients with recurrent... read more	Click for more details and contact information
Medulloblastoma	A dose finding and safety study of Oral LDE225 in children	Interventional: drug. This study is to decide what the maximum tolerated dose of LDE225 is and to characterise the limiting toxicities of LDE225 read more	Click for more details and contact information
Glioma	CNS 2004 03 Cooperative multicentre study for children and adolescents with low grade glioma.	Interventional: chemo. This trial is looking at chemotherapy and radiotherapy for children and young people with a 'low grade' tumour. If possible, children and... read more	Click for more details and contact information
Glioblastoma	CRUKD/11/006: OPERATIC A Cancer Research UK Trial of olaparib (AZD2281), an oral PARP inhibitor, combined with extended low-dose oral temozolomide in patients with relapsed glioblastoma	Interventional: drug. The aims of this study of AZD2281 in combination with extended, daily low-dose temozolomide in patients with recurrent GBM is proposed are... read more	Click for more details and contact information
Glioma	CNS 2007 13 Translational Study for Children and Adolescents with Low Grade Glioma	Observational. This study is looking at the family histories of children and young people who have been diagnosed with a low grade glioma. Researchers are trying to... read more	Click for more details and contact information
Glioblastoma	ISRCTN62033854 Magnetic resonance imaging to characterise invasive phenotypes in cerebral gliomas: an observational prospective cohort study	An observational study using imaging. The spectrum of high grade gliomas invasion can be identified using diffusion tensor imaging (DTI). Combining these findings... read more	Click for more details and contact information
Glioblastoma	DORIC - Phase II trial of cediranib +/- gefitinib for recurrent glioblastoma	Interventional: drug. This is a randomised, double blind placebo controlled study in patients with recurrent or progressive glioblastoma (WHO grade IV). Patients are... read more	Click for more details and contact information
Glioma	CRUK/07/032: BR13: Primary chemotherapy with temozolomide vs radiotherapy in patients with low-grade gliomas after stratification for genetic 1p loss: a phase III study (EORTC 22033-26033)	A randomized study to demonstrate a difference in progression-fre survival (PFS) for primary treatment with temozolomide in order to assess: whether PFS and overall... read more	Click for more details and contact information
Glioblastoma	NCT00977431 Open Label Trial to Explore Safety of Combining Afatinib (BIBW 2992) and Radiotherapy With or Without Temozolomide in Newly Diagnosed Glioblastoma Multiforme	Interventional: drug and radiotherapy. This study is an open label trial to determine the Maximum Tolerated Dose (MTD), safety, pharmacokinetics, and efficacy of BIBW... read more	Click for more details and contact information
Glioblastoma	Dose-Escalation Study of Carboplatin Administration Into the Brain for Glioblastoma Multiforme NCT01317212	This is a phase 1 trial. Laboratory studies demonstrate that glioma tumour cells are sensitive to a number of different chemotherapies, including carboplatin. When... read more	Click for more details and contact information
Ependymoma	Erlotinib Versus Oral Etoposide in Patients With Recurrent or Refractory Pediatric Ependymoma (PETEY) NCT01032070	This is a phase 2 study to evaluate the efficacy of single-agent erlotinib versus oral etoposide in patients with recurrent or refractory pediatric ependymoma. It is... read more	Click for more details and contact information
Meningioma Glioma	A study to see if a type of MRI scan can help doctors planning surgery to treat brain tumours	Observational. The main aim of this study is to see how useful fMRI is to map parts of the brain. Researchers want to test a new way of finding out whether the tumour... read more	Click for more details and contact information
Anaplastic astrocytoma Anaplastic glioma Anaplastic oligodendroglioma Astrocytoma Glioblastoma Glioma Medulloblastoma Meningioma	UKCRN ID 9977 An Evaluation of a Patient Information Navigation Service: Informing and involving newly diagnosed malignant brain tumour and colorectal cancer patients in their cancer health care using a Patient Information Navigator.	For Scottish patients, this study utilises the decision model already piloted in the Edinburgh Cancer Centre with Breast and Prostate Cancer patients. This model... read more	Click for more details and contact information
Anaplastic oligodendroglioma Astrocytoma Glioma Medulloblastoma Meningioma	MREC - 07/MRC10/11 National Brain Tumour Study (NBT)	Observational. The purpose of the National Brain Tumour Study (NBT) this study is to establish a DNA resource from individuals and families with brain tumours,... read more	Click for more details and contact information
Glioblastoma	Phase 1 clinical trial of olaparib with temozolomide in recurrent glioblastoma	In this trial, they are looking at a drug called olaparib which is a biological therapy called a PARP inhibitor. PARP is an enzyme that helps damaged cells to repair... read more	Click for more details and contact information

View by brain tumour type: All brain tumour types , Anaplastic astrocytoma, Anaplastic glioma, Anaplastic oligodendroglioma, Astrocytoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Ependymoma

Brain tumour clinical trials available for: All brain tumour types

Brain tumour clinical trials available for:
All brain tumour types